Endocrine Abstracts

An 22-year-old patient with a history of homozygous sickle cell disease (complicated by multiple vaso-occlusive attacks) was referred to the endocrinologist for persistent hypercalcemia for more than one year (between 2.63 and 2.82 mmol/l, N: 2.15–2.50 mmol/l), associated with hypophosphoremia (0.71 mmol/l, N: 0.75–1.39 mmol/l) and elevation of parathyroid hormone (170 ng/l, N <49 ng/l). Cervical ultrasound did not show parathyroid adenoma, but parathyroid MIBI s...

Background and aim: Insulin tolerance test (ITT) is the gold standard for the diagnosis of cortisol and growth hormone deficiencies in adults. Once hypoglycaemia (<40 mg/dl) is achieved, some medical centers give sugar to their patients (food, drink or glucose infusion), others do not and let the blood glucose rise spontaneously. Although critical hypoglycaemia results in discomfort and potential complications for the patients there is so far no recommendation on the subje...

Introduction: In 30–50% of cases central diabetes insipidus (CDI) is idiopathic. Other causes include tumours, pituitary surgery, cranial trauma or infiltrative diseases. Long-term medical follow-up is crucial given that idiopathic CDI can be the earliest sign of an evolving process (inflammatory or tumoural).Case report: We report the case of a 23-year-old woman who presented with isolated polydipsia and polyuria. The diagnosis of isolated CDI was ...